New Paper: ZBTB7B (ThPOK) Is Required for Pathogenesis of Cerebral Malaria and Protection Against Pulmonary Tuberculosis

Illustration Paper Dr. Gros Dec. 2019

Congratulations to Platform 1 Co-Lead Dr. Philippe Gros on this recent publication! Abstract We have used a genome-wide screen in N-ethyl-N-nitrosourea (ENU) mutagenized mice to identify genes in which recessive loss of function mutations protect against pathological neuroinflammation. We identified an R367Q mutation in the ZBTB7B (ThPOK) protein which homozygosity causes protection against experimental cerebral malaria […]