New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores for bone mineral density have demonstrated potential clinical utility. However, the value of rare genetic determinants in risk prediction has not been assessed. With whole-exome sequencing data from 436,824 UK […]
New Paper: Moving Beyond Descriptive Studies: Harnessing Metabolomics to Elucidate the Molecular Mechanisms Underpinning Host-Microbiome Phenotypes
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj & our Platform 4 Co-Lead Dr. Ian Lewis on this recent publication! Abstract Advances in technology and software have radically expanded the scope of metabolomics studies and allow us to monitor a broad transect of central carbon metabolism in routine studies. These increasingly sophisticated tools have […]
IMPACTT Microbiome Standards & Benchmarking
IMPACTT Microbiome Standards & Benchmarking IMPACTT Microbiome Standards What’s in our standards? A community of 45 bacterial species that are phylogenetically diverse and evenly distributed Novel, sequenced strains Encased in human fecal matrix (3 types) or PBS (1 type) Watch our video to learn more Fill out the form and get the standards What makes […]
Introducing: IMPACTT Microbiome Standards
We are excited to introduce our IMPACTT Microbiome Standards! A defined microbial community of 45 phylogenetically diverse, evenly distributed bacteria encased in human fecal matrix or PBS. The best part: it’s free for Canadian labs! This initiative is led by our Platform 4 Lead Dr. Laura Sycuro (University of Calgary), who partnered with Dr. Emma […]
New Paper: Beta-Diversity Distance Matrices for Microbiome Sample Size and Power Calculations — How to Obtain Good Estimates
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, as well as Platform 2 Leads Dr. Anita Kozyrskyj & Dr. Marie-Claire Arrieta, Platform 5 Lead Dr. Celia Greenwood, and Sex & Gender Lead Dr. Jayne Danska on this recent publication! Abstract In microbiome studies, researchers often wish to compare the taxa count distributions between […]
Bioinformatics Workshop
IMPACTT Bioinformatics Workshop About the Workshop Our workshops in 2022 and 2023 provided an introduction to marker-gene analysis, metagenomic, and metatranscriptomic data analysis followed by hands-on practical tutorials for each session to demonstrate the use of relevant bioinformatics and statistical tools. Modules consisted of lectures covering both theoretical and practical components followed by hands-on bioinformatic […]
