New Paper: From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! This recent study from Dr. Kozyrskyj’s team and colleagues highlights how birth factors from the CHILD study cohort (@CHILDSTUDY) correlate to changes in the gut microbes of infants to “determine the pathways by which these alterations may lead to an increased risk […]
New Paper: Innate Responses to Gut Microbiota; Critical Assessment of the Necessary Experimental Controls
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Focusing on the recent findings (since 2017) regarding the commensal bacteria of the mouse intestinal tract, Dr. McCoy and Dr. Ohland discuss the importance and advances of what experimental controls are required to reliably determine how the microbiota influences the […]
New Paper: Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy, as well as our Education & Mentorship Lead & Co-Lead Dr. Markus Geuking and Dr. Braedon McDonald, on this recent publication! Summary Eradication of pathogens from the bloodstream is critical to prevent disseminated infections and sepsis. Kupffer cells in the liver form an intravascular […]
New Paper: Vitamin D Supplementation in Pregnancy and Early Infancy in Relation to Gut Microbiota Composition and C. difficile Colonization: Implications for Viral Respiratory Infections
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Studying 1,157 mother-infant pairs of the CHILD Cohort, researchers unravel a possible link between vitamin D supplementation during early-life and protection against C. difficile infection. Vit-D supplementation was also observed to be associated with a lower level of a specific bacterium Megamonas. […]
New Paper: Sex-Specific Differences in the Gut Microbiome in Response to Dietary Fiber Supplementation in IL-10-Deficient Mice
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Using (IL)-10 deficient murine colitis model, Dr. Zhang et al. investigated whether the effects of isomaltodextrin (IMD) on gut microbiota and IBD were dependent on dose or host sex. Abstract There is growing interest in studying dietary fiber to stimulate microbiome changes […]
New Paper: Sleep, Circadian Rhythm, and Gut Microbiota
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! In this clinical review, Dr. Matenchuk, Dr. Mandhane and Dr. Kozyrskyj gathered recent discoveries about the relationship between sleep, circadian rhythm and the gut microbiome. Building on the work of Krueger and Opp, 2016 and Broussard et al., 2016, the authors consolidate the current literature on this relationship. […]
