New Paper: From Germ-Free to Wild: Modulating Microbiome Complexity to Understand Mucosal Immunology
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract The gut microbiota influences host responses at practically every level, and as research into host-microbe interactions expands, it is not surprising that we are uncovering similar roles for the microbiota at other barrier sites, such as the lung […]
New Paper: Metaproteomic Profiling of Fungal Gut Colonization in Gnotobiotic Mice
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Eukaryotic microbes can modulate mammalian host health and disease states, yet the molecular contribution of gut fungi remains nascent. We previously showed that mice exclusively colonised with fungi displayed increased sensitivity to allergic airway inflammation and had fecal metabolite profiles similar […]
Gnotobiotic Workshop
IMPACTT/IMC Gnotobiotic Workshop About the Workshop Stay Updated This 2.5 day hands-on workshop is for any student, PI, researcher, or tech who wants to learn how to conduct gnotobiotic and germ-free animal experiments. Over the course of this workshop you will learn to set up, sterilize, and maintain a germ-free isolator. You will gain the […]
Exploring the Microbiome with @MediaplanetCA
From health and disease to unravelling the Microbiome of extreme environments, this special campaign by Media Planet highlights cutting-edge and promising microbiome research and technical expertise across Canada. Notably featured is the International Microbiome Centre (IMC), based out of the University of Calgary and led by our IMPACTT Director Dr. Kathy McCoy. The IMC is […]
Protocol: Generation, Maintenance, and Monitoring of Gnotobiotic Mice
Summary Gnotobiology has revolutionized the study of microbiota-host interactions. This protocol explains how to generate, maintain, and monitor gnotobiotic mice. Three monitoring methods are presented and compared: bacterial culture, microscopy to visualize the presence (or absence) of bacteria using Gram staining or DNA staining, and 16S rRNA gene amplification and sequencing. The generation and maintenance […]
Platform 1 | Resources
Platform 1 Resources Keep scrolling for posts and pages related to our Platform 1 on Gnotobiotic Animals & Intravital Microscopy. Related Posts Related Pages
