New Paper: Moving Beyond Descriptive Studies: Harnessing Metabolomics to Elucidate the Molecular Mechanisms Underpinning Host-Microbiome Phenotypes

Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj & our Platform 4 Co-Lead Dr. Ian Lewis on this recent publication! Abstract Advances in technology and software have radically expanded the scope of metabolomics studies and allow us to monitor a broad transect of central carbon metabolism in routine studies. These increasingly sophisticated tools have […]

IMPACTT Microbiome Standards & Benchmarking

IMPACTT Microbiome Standards & Benchmarking IMPACTT Microbiome Standards What’s in our standards? A community of 45 bacterial species that are phylogenetically diverse and evenly distributed Novel, sequenced strains Encased in human fecal matrix (3 types) or PBS (1 type) Watch our video to learn more Fill out the form and get the standards What makes […]

Introducing: IMPACTT Microbiome Standards

We are excited to introduce our IMPACTT Microbiome Standards! A defined microbial community of 45 phylogenetically diverse, evenly distributed bacteria encased in human fecal matrix or PBS. The best part: it’s free for Canadian labs! This initiative is led by our Platform 4 Lead Dr. Laura Sycuro (University of Calgary), who partnered with Dr. Emma […]

New Paper: Metaproteomic Profiling of Fungal Gut Colonization in Gnotobiotic Mice

Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Eukaryotic microbes can modulate mammalian host health and disease states, yet the molecular contribution of gut fungi remains nascent. We previously showed that mice exclusively colonised with fungi displayed increased sensitivity to allergic airway inflammation and had fecal metabolite profiles similar […]

New Paper: Protease Activities of Vaginal Porphyromonas Species Disrupt Coagulation and Extracellular Matrix in the Cervicovaginal Niche

Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Porphyromonas asaccharolytica and Porphyromonas uenonis are common inhabitants of the vaginal microbiome, but their presence has been linked to adverse health outcomes for women, including bacterial vaginosis and preterm birth. However, little is known about the pathogenesis mechanisms of these bacteria. The related oral […]

Platform 4 | Resources

Platform 4 Resources Keep scrolling for posts and pages related to our Platform 4 on Functional Omics. Related Posts Related Pages