New Paper: Mucosal or Systemic Microbiota Exposures Shape the B Cell Repertoire
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! In this intercontinental research effort between Switzerland, Norway, Germany and Canada, Dr. H. Li, colleagues and international collaborators notably Dr. K.D. McCoy, used “localized time-limited exposures of defined doses of single benign microbial taxa in germ-free mice” to “address how […]
New Paper: Sex-Specific Differences in the Gut Microbiome in Response to Dietary Fiber Supplementation in IL-10-Deficient Mice
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Using (IL)-10 deficient murine colitis model, Dr. Zhang et al. investigated whether the effects of isomaltodextrin (IMD) on gut microbiota and IBD were dependent on dose or host sex. Abstract There is growing interest in studying dietary fiber to stimulate microbiome changes […]
New Paper: Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases.
Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.
New Paper: Perivascular Localization of Macrophages in the Intestinal Mucosa is Regulated by Nr4a1 and the Microbiome
A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.
The emerging roles of eosinophils in mucosal homeostasis.
A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.
New Paper: Immunological Roles of Intestinal Mesenchymal Cells
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract The intestine is continuously exposed to an enormous variety and quantity of antigens and innate immune stimuli derived from both pathogens and harmless materials, such as food and commensal bacteria. Accordingly, the intestinal immune system is uniquely adapted […]
