New Paper: Ethical Health Security in the Age of Antimicrobial Resistance

Congratulations to our Ethics Lead Dr. Diego Silva on this recent publication! Abstract Owing to its potential human, social and economic costs, antimicrobial resistance (AMR) is frequently referred to as a threat to health security. Simultaneously, health security and the preservation of antimicrobials are often described as a global public good. However, how the term […]

New Paper: Metaproteomic Profiling of Fungal Gut Colonization in Gnotobiotic Mice

Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Eukaryotic microbes can modulate mammalian host health and disease states, yet the molecular contribution of gut fungi remains nascent. We previously showed that mice exclusively colonised with fungi displayed increased sensitivity to allergic airway inflammation and had fecal metabolite profiles similar […]

New Paper: Protease Activities of Vaginal Porphyromonas Species Disrupt Coagulation and Extracellular Matrix in the Cervicovaginal Niche

Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Porphyromonas asaccharolytica and Porphyromonas uenonis are common inhabitants of the vaginal microbiome, but their presence has been linked to adverse health outcomes for women, including bacterial vaginosis and preterm birth. However, little is known about the pathogenesis mechanisms of these bacteria. The related oral […]

Role and Impact of the Microbiome on the Human Genome

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Read about key concepts and views on the role and impact of our microbes’ genomes on our human genome! 3 recent papers to give you Food For Thought Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes. Theis R. K., et al. mSystems. Mar 2016.  ABSTRACTGiven the complexity of host-microbiota symbioses, scientists and […]