New Paper: The Hygiene Hypothesis, the COVID Pandemic, and Consequences for the Human Microbiome
Congratulations to our Platform 1 Co-Lead Dr. Philippe Gros on this recent publication! A perspective from the Canadian Institute for Advanced Research (CIFAR) on the impact of the environment related to the COVID pandemic and its effects on the human microbiome. Explore many facets of COVID-19−induced societal changes and their possible effects on the microbiome, and […]
New Paper: Maternal Consumption of Artificially Sweetened Beverages During Pregnancy is Associated with Infant Gut Microbiota and Metabolic Modifications and Increased Infant Body Mass Index
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta and our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Studying 100 infants from the CHILD Cohort Study, the authors aim to understand the link observed between the rise in childhood obesity and sweetener consumption during pregnancy. Abstract Artificial sweetener consumption by pregnant women […]
New Paper: From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! This recent study from Dr. Kozyrskyj’s team and colleagues highlights how birth factors from the CHILD study cohort (@CHILDSTUDY) correlate to changes in the gut microbes of infants to “determine the pathways by which these alterations may lead to an increased risk […]
New Paper: Innate Responses to Gut Microbiota; Critical Assessment of the Necessary Experimental Controls
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Focusing on the recent findings (since 2017) regarding the commensal bacteria of the mouse intestinal tract, Dr. McCoy and Dr. Ohland discuss the importance and advances of what experimental controls are required to reliably determine how the microbiota influences the […]
New Paper: Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Using in vivo live imaging of infected lungs in animal models, Dr. Kubes‘ team and colleagues show that alveolar macrophages patrol the airways and capture inhaled bacteria, but their migration is impaired during viral infection. Their discoveries highlight the importance of finding […]
New Paper: Microbial Modulation of Intestinal T Helper Cell Responses and Implications for Disease and Therapy
Congratulations to our Education & Mentorship Lead Dr. Markus Geuking on this recent publication! This review summarizes the milestone findings in the field of microbiota-intestinal T helper cell crosstalk with a focus on the role of specific commensal bacteria and their metabolites. They discuss mechanistic mouse studies and are linking these to human studies where […]