Documentary: Let Them Eat Dirt

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Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children from an Oversanitized World. In the book, they explain how the millions of microbes that live in our bodies influence childhood development, and why an imbalance in those microbes can […]

Protocol: Generation, Maintenance, and Monitoring of Gnotobiotic Mice

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Summary Gnotobiology has revolutionized the study of microbiota-host interactions. This protocol explains how to generate, maintain, and monitor gnotobiotic mice. Three monitoring methods are presented and compared: bacterial culture, microscopy to visualize the presence (or absence) of bacteria using Gram staining or DNA staining, and 16S rRNA gene amplification and sequencing. The generation and maintenance […]

Video: Host-Microbe-Environment Interactions

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Over the past few years, evidence has revealed the key role that microbes play in human health and disease. This short animated video highlights key concepts that are considered in research to understand the intrinsic host-microbe-environment relationships and enable researchers to harness this knowledge to improve our health. This short animated video highlights key concepts […]

Role and Impact of the Microbiome on the Human Genome

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Read about key concepts and views on the role and impact of our microbes’ genomes on our human genome! 3 recent papers to give you Food For Thought Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes. Theis R. K., et al. mSystems. Mar 2016.  ABSTRACTGiven the complexity of host-microbiota symbioses, scientists and […]

Platform 2 | Resources

Platform 2 Resources Keep scrolling for posts and pages related to our Platform 2 on Human Cohort Design & Analysis. Related Posts Related Pages

Platform 5 | Resources

Platform 5 Resources Keep scrolling for posts and pages related to our Platform 5 on Computational Development. Related Posts Related Pages