New Paper: The Rise to Power of the Microbiome: Power and Sample Size Calculation for Microbiome Studies
Congratulations to our Platform 2 Leads Dr. Marie-Claire Arrieta & Dr. Anita Kozyrskyj, and Platform 5 Lead Dr. Celia Greenwood, on this recent publication! Abstract A priori power and sample size calculations are crucial to appropriately test null hypotheses and obtain valid conclusions from all clinical studies. Statistical tests to evaluate hypotheses in microbiome studies […]
New Paper: The Hygiene Hypothesis, the COVID Pandemic, and Consequences for the Human Microbiome
Congratulations to our Platform 1 Co-Lead Dr. Philippe Gros on this recent publication! A perspective from the Canadian Institute for Advanced Research (CIFAR) on the impact of the environment related to the COVID pandemic and its effects on the human microbiome. Explore many facets of COVID-19−induced societal changes and their possible effects on the microbiome, and […]
New Paper: Innate Responses to Gut Microbiota; Critical Assessment of the Necessary Experimental Controls
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Focusing on the recent findings (since 2017) regarding the commensal bacteria of the mouse intestinal tract, Dr. McCoy and Dr. Ohland discuss the importance and advances of what experimental controls are required to reliably determine how the microbiota influences the […]
New Paper: Sex-Specific Differences in the Gut Microbiome in Response to Dietary Fiber Supplementation in IL-10-Deficient Mice
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Using (IL)-10 deficient murine colitis model, Dr. Zhang et al. investigated whether the effects of isomaltodextrin (IMD) on gut microbiota and IBD were dependent on dose or host sex. Abstract There is growing interest in studying dietary fiber to stimulate microbiome changes […]
New Paper: Sleep, Circadian Rhythm, and Gut Microbiota
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! In this clinical review, Dr. Matenchuk, Dr. Mandhane and Dr. Kozyrskyj gathered recent discoveries about the relationship between sleep, circadian rhythm and the gut microbiome. Building on the work of Krueger and Opp, 2016 and Broussard et al., 2016, the authors consolidate the current literature on this relationship. […]
The impact of maternal and early life malnutrition on health: a diet-microbe perspective.
Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.