Improve Human Immunology Research with CAN-ASC
The Canadian Autoimmunity Standardization Core (CAN-ASC) was funded in 2018 by the Canadian Institutes of Health Research (CIHR) in order to provide guidance on best practices in human immunology research, focusing on methods in translational autoimmune research. Led by Dr. Megan Levings, CAN-ASC team members are a consortium of Canadian researchers and clinician-scientists who are experts in clinical […]
Sex & Gender | Resources
Sex & Gender Resources Keep scrolling for posts and pages related to our Sex & Gender Platform. Related Posts Related Pages
The 4 Core Genotype Model
The 4 Core Genotype (4CG) Model This murine model enables researchers to distinguish sex hormone effects from sex chromosome effects in their research. Below is a description of the characteristics of this model. The 4CG model will soon be made available under gnotobiotic conditions at the International Microbiome Centre in Calgary upon request. Request the […]
New Paper: Sex-Specific Differences in the Gut Microbiome in Response to Dietary Fiber Supplementation in IL-10-Deficient Mice
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Using (IL)-10 deficient murine colitis model, Dr. Zhang et al. investigated whether the effects of isomaltodextrin (IMD) on gut microbiota and IBD were dependent on dose or host sex. Abstract There is growing interest in studying dietary fiber to stimulate microbiome changes […]
IMPACTT Sex & Gender Reading Pick
Sex: A change in our guidelines to authors to ensure that this is no longer an ignored variable An article by James R. Docherty et al., published 23 August 2019 in the British Journal of Pharmacology Communication from IMPACTT Sex & Gender Lead Dr. Jayne Danska At a time when precision medicine is a strategic […]
Sex & Gender | Platform
Sex & Gender Our Sex & Gender Expert Dr. Jayne Danska “Ensure that sex and gender are considered in experimental design to improve understanding of fundamental biological mechanisms of future Canadian microbiome studies.” Statement There are known sex and gender differences in the susceptibility, severity, and symptom expression of diseases, as well as differences in […]
