New Paper: Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Using a define mouse model of acute methicillin-resistant Staphylococcus aureus (MRSA) bacteremia along with intravital microscopy, Deppermann C, et al. unravelled why Tacrolimus, a drug used to prevent rejection in solid organ transplant recipients increases the susceptibility of transplant recipient to develop […]
New Paper: Fecal Transplant Prevents Gut Dysbiosis and Anxiety-Like Behaviour After Spinal Cord Injury in Rats
A model of anxiety following a cervical contusion spinal cord injury in rats demonstrates fecal transplant prevents gut dysbiosis and anxiety-like behaviour
New Paper: Intestinal Fungi are Causally Implicated in Microbiome Assembly and Immune Development in Mice
Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.
New Paper: Perivascular Localization of Macrophages in the Intestinal Mucosa is Regulated by Nr4a1 and the Microbiome
A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.
The emerging roles of eosinophils in mucosal homeostasis.
A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.
New Paper: Immunological Roles of Intestinal Mesenchymal Cells
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract The intestine is continuously exposed to an enormous variety and quantity of antigens and innate immune stimuli derived from both pathogens and harmless materials, such as food and commensal bacteria. Accordingly, the intestinal immune system is uniquely adapted […]
